Do viruses become milder over time?

The short answer is yes. However, they don’t do that because they ‘want’ to live longer inside patients. Viruses have no free will. Rather, the process is called survival of the fittest – the backbone of classical evolution theory.

It was already well-known when I was a medical student, almost half a century ago, that over time, viral and bacterial infections become less vicious to a population. And the mechanism is not complicated.

Genetic material in microbes is more sensitive to (random) persistent mutations than the DNA and RNA of more complex organisms. These genetically slightly different microscopic siblings may have slightly different effects on patients. Now, the toughest ones kill off their hosts in no time and then their days are numbered — till a few hours after death. If they don’t succeed to infect others during the short sickbed and the day after death, they die out with their victim. But variants that have a better survival rate are those that make the patient less sick, less quickly (so they stay up, out and about, infecting others) and preferably don’t kill — because as long as there is life to parasite on, there is hope to spread.

So, the virus doesn’t calculate and doesn’t understand which would be its smartest behavior. The nicer ones just are spread earlier and longer.

And this is how, overall, microbial infections over time get milder but make more people sick. The seasonal flu is a good example of a virus that’s generally not as dangerous anymore. But it is so contagious that lockdown wouldn’t stop it. But it doesn’t kill as many people as does the newest coronavirus so far. Meanwhile, at the beginning of getting milder, the virus may still kill even more people than before, as I’ve explained before.

COVID-19 has one trick up its sleeve that is far superior to most agents of infection. The host spreads it best before s/he feels sick at all. I don’t think that it ‘wants’ to give that one up. That means that our best hope against this epidemic is prevention through vaccination. Smart people take little risk until safe and potent vaccines will be ready and available.

Meanwhile, don’t forget that this virus does much more than spread and kill. It can take people down for months. Even healthy young people, who were hardly sick at first. Many of them went from full-time workers and athletes to being chronically exhausted already for three months. Medical scientists sometimes are so anxious about death that they forget that there is more to well-being than not dying. There is a good reason for the younger and the healthiest people too to try and avoid getting infected.

About the Author

MM is a prolific and creative writer and thinker, previously a daily blog contributor to the TOI. He often makes his readers laugh, mad, or assume he's nuts—close to perfect blogging. He's proud that his analytical short comments are removed both from left-wing and right-wing news sites. None of his content is generated by the new bore on the block, AI. * As a frontier thinker, he sees things many don't yet. He's half a prophet. Half. Let's not exaggerate. Or not at all because he doesn't claim G^d talks to him. He gives him good ideas—that's all. MM doesn't believe that people observe and think in a vacuum. He, therefore, wanted a broad bio that readers interested can track a bit what (lack of) backgrounds, experiences, and educations contribute to his visions. * This year, he will prioritize getting his unpublished books published rather than just blog posts. Next year, he hopes to focus on activism against human extinction. To find less-recent posts on a subject XXX among his over 2000 archived ones, go to the right-top corner of a Times of Israel page, click on the search icon and search "zuiden, XXX". One can find a second, wilder blog, to which one may subscribe too, here: https://mmvanzuiden.wordpress.com/ or by clicking on the globe icon next to his picture on top. * Like most of his readers, he believes in being friendly, respectful, and loyal. However, if you think those are his absolute top priorities, you might end up disappointed. His first loyalty is to the truth. He will try to stay within the limits of democratic and Jewish law, but he won't lie to support opinions or people when don't deserve that. (Yet, we all make honest mistakes, which is just fine and does not justify losing support.) He admits that he sometimes exaggerates to make a point, which could have him come across as nasty, while in actuality, he's quite a lovely person to interact with. He holds - how Dutch - that a strong opinion doesn't imply intolerance of other views. * Sometimes he's misunderstood because his wide and diverse field of vision seldomly fits any specialist's box. But that's exactly what some love about him. He has written a lot about Psychology (including Sexuality and Abuse), Medicine (including physical immortality), Science (including basic statistics), Politics (Israel, the US, and the Netherlands, Activism - more than leftwing or rightwing, he hopes to highlight reality), Oppression and Liberation (intersectionally, for young people, the elderly, non-Whites, women, workers, Jews, LGBTQIA+, foreigners and anyone else who's dehumanized or exploited), Integrity, Philosophy, Jews (Judaism, Zionism, Holocaust and Jewish Liberation), the Climate Crisis, Ecology and Veganism, Affairs from the news, or the Torah Portion of the Week, or new insights that suddenly befell him. * Chronologically, his most influential teachers are his parents, Nico (natan) van Zuiden and Betty (beisye) Nieweg, Wim Kan, Mozart, Harvey Jackins, Marshal Rosenberg, Reb Shlomo Carlebach, and, lehavdil bein chayim lechayim, Rabbi Dr. Natan Lopes Cardozo, Rav Zev Leff, and Rav Meir Lubin. This short list doesn't mean to disrespect others who taught him a lot or a little. One of his rabbis calls him Mr. Innovation [Ish haChidushim]. Yet, his originalities seem to root deeply in traditional Judaism, though they may grow in unexpected directions. In fact, he claims he's modernizing nothing. Rather, mainly basing himself on the basic Hebrew Torah text, he tries to rediscover classical Jewish thought almost lost in thousands of years of stifling Gentile domination and Jewish assimilation. (He pleads for a close reading of the Torah instead of going by rough assumptions of what it would probably mean and before fleeing to Commentaries.) This, in all aspects of life, but prominently in the areas of Free Will, Activism, Homosexuality for men, and Redemption. * He hopes that his words will inspire and inform, and disturb the comfortable and comfort the disturbed. He aims to bring a fresh perspective rather than harp on the obvious and familiar. When he can, he loves to write encyclopedic overviews. He doesn't expect his readers to agree. Rather, original minds should be disputed. In short, his main political positions are among others: anti-Trumpism, for Zionism, Intersectionality, non-violence, anti those who abuse democratic liberties, anti the fake ME peace process, for original-Orthodoxy, pro-Science, pro-Free Will, anti-blaming-the-victim, and for down-to-earth, classical optimism, and happiness. Read his blog on how he attempts to bridge any tensions between those ideas or fields. * He is a fetal survivor of the pharmaceutical industry (https://diethylstilbestrol.co.uk/studies/des-and-psychological-health/), born in 1953 to his parents who were Dutch-Jewish Holocaust survivors who met in the largest concentration camp in the Netherlands, Westerbork. He grew up a humble listener. It took him decades to become a speaker too, and decades more to admit to being a genius. But his humility was his to keep. And so was his honesty. Bullies and con artists almost instantaneously envy and hate him. He hopes to bring new things and not just preach to the choir. * He holds a BA in medicine (University of Amsterdam) – is half a doctor. He practices Re-evaluation Co-counseling since 1977, is not an official teacher anymore, and became a friendly, powerful therapist. He became a social activist, became religious, made Aliyah, and raised three wonderful kids. Previously, for decades, he was known to the Jerusalem Post readers as a frequent letter writer. For a couple of years, he was active in hasbara to the Dutch-speaking public. He wrote an unpublished tome about Jewish Free Will. He's a strict vegan since 2008. He's an Orthodox Jew but not a rabbi. * His writing has been made possible by an allowance for second-generation Holocaust survivors from the Netherlands. It has been his dream since he was 38 to try to make a difference by teaching through writing. He had three times 9-out-of-10 for Dutch at his high school finals but is spending his days communicating in English and Hebrew - how ironic. G-d must have a fine sense of humor. In case you wonder - yes, he is a bit dyslectic. If you're a native English speaker and wonder why you should read from people whose English is only their second language, consider the advantage of having an original peek outside of your cultural bubble. * To send any personal reaction to him, scroll to the top of the blog post and click Contact Me. * His newest books you may find here: https://www.amazon.com/s?i=stripbooks&rh=p_27%3AMoshe-Mordechai%2FMaurits+van+Zuiden&s=relevancerank&text=Moshe-Mordechai%2FMaurits+van+Zuiden&ref=dp_byline_sr_book_1